| 09/10/05 | hosting | Franklin | 23-41 |
| 09/17/05 | at | Ohio Wesleyan | 7-21 |
| 09/24/05 | at | Manchester | 40-7 |
| 10/01/05 | at | Alma | 24-49 |
| 10/08/05 | hosting | Hope | 31-24 |
| 10/15/05 | at | Adrian | 31-37 |
| 10/22/05 | hosting | Tri-State | 42-26 |
| 10/29/05 | hosting | Kalamazoo | 20-14 |
| 11/05/05 | at | Wisconsin Lutheran | 28-14 |
| 11/12/05 | hosting | Albion | 19-36 |