| 09/10/05 | hosting | Greenville | 26-17 |
| 09/17/05 | at | Urbana | 31-39 |
| 09/24/05 | hosting | Walsh | 3-31 |
| 10/01/05 | at | Olivet Nazarene | 6-33 |
| 10/08/05 | hosting | St Ambrose | 18-40 |
| 10/15/05 | at | St Francis IL | 42-7 |
| 10/22/05 | at | Iowa Wesleyan | 14-3 |
| 10/29/05 | hosting | St Xavier | 21-55 |
| 11/05/05 | at | William Penn | 6-30 |
| 11/12/05 | hosting | McKendree | 6-23 |