| 09/03/05 | hosting | Quincy | 44-0 |
| 09/17/05 | at | St Francis IN | 21-28 |
| 09/24/05 | hosting | Ohio Dominican | 52-0 |
| 10/01/05 | hosting | Iowa Wesleyan | 52-0 |
| 10/08/05 | at | St Xavier | 14-21 |
| 10/15/05 | at | William Penn | 12-6 |
| 10/22/05 | hosting | St Francis IL | 27-3 |
| 10/29/05 | at | Olivet Nazarene | 19-9 |
| 11/05/05 | hosting | St Ambrose | 41-9 |
| 11/12/05 | at | Trinity Int'l | 23-6 |
| 11/19/05 | hosting | Evangel | 31-34 |