| 09/03/05 | at | McKendree | 0-44 |
| 09/10/05 | at | Missouri St | 14-51 |
| 09/17/05 | hosting | Iowa Wesleyan | 21-16 |
| 09/24/05 | at | William Penn | 24-38 |
| 10/01/05 | hosting | Taylor | 26-19 |
| 10/08/05 | at | Walsh | 26-31 |
| 10/15/05 | at | Geneva | 21-52 |
| 10/22/05 | hosting | Ohio Dominican | 24-14 |
| 10/29/05 | hosting | Urbana | 45-30 |
| 11/05/05 | at | St Francis IN | 19-53 |
| 11/12/05 | hosting | Malone | 48-9 |