| 11/13/06 | vs. | Lafayette | 91-66 |
| 11/14/06 | at | Butler | 55-60 |
| 11/17/06 | hosting | Indiana St. | 73-66 |
| 11/19/06 | hosting | Chicago St. | 90-69 |
| 11/28/06 | at | Duke | 51-54 |
| 12/02/06 | hosting | Charlotte | 74-57 |
| 12/06/06 | hosting | Western Illinois | 92-40 |
| 12/09/06 | at | Kentucky | 54-59 |
| 12/17/06 | hosting | Southern Illinois | 57-47 |
| 12/20/06 | hosting | Western Michigan | 77-69 |
| 12/22/06 | vs. | IUPUI | 86-57 |
| 12/30/06 | hosting | Ball St. | 71-57 |
| 01/02/07 | at | Ohio St. | 67-74 |
| 01/07/07 | hosting | Michigan St. | 73-51 |
| 01/10/07 | hosting | Purdue | 85-58 |
| 01/13/07 | at | Penn St. | 84-74 |
| 01/16/07 | hosting | Iowa | 71-64 |
| 01/20/07 | at | Connecticut | 77-73 |
| 01/23/07 | at | Illinois | 43-51 |
| 01/27/07 | hosting | Michigan | 76-61 |
| 01/31/07 | hosting | Wisconsin | 71-66 |
| 02/03/07 | at | Iowa | 75-81 |
| 02/10/07 | hosting | Illinois | 65-61 |
| 02/15/07 | at | Purdue | 68-81 |
| 02/17/07 | at | Michigan | 55-58 |
| 02/21/07 | hosting | Minnesota | 71-59 |
| 02/24/07 | at | Michigan St. | 58-66 |
| 02/28/07 | at | Northwestern | 69-65 |
| 03/03/07 | hosting | Penn St. | 94-63 |
| 03/09/07 | vs. | Illinois | 54-58 OT |
| 03/15/07 | vs. | Gonzaga | 70-57 |
| 03/17/07 | vs. | UCLA | 49-54 |