| (49.92) | ||||
| 03/29/08 | at | Colorado Rapids | (49.96) | 0-4 |
| 04/03/08 | hosting | San Jose Earthquakes | (49.65) | 2-0 |
| 04/13/08 | hosting | Toronto FC | (49.96) | 2-3 |
| 04/19/08 | hosting | Houston Dynamo | (50.04) | 2-2 |
| 04/26/08 | hosting | Chivas USA | (49.94) | 5-2 |
| 05/03/08 | at | Real Salt Lake | (49.95) | 2-2 |
| 05/10/08 | hosting | New York Red Bulls | (50.01) | 1-2 |
| 05/18/08 | at | FC Dallas | (50.07) | 5-1 |
| 05/24/08 | hosting | Kansas City Wizards | (49.85) | 3-1 |
| 05/31/08 | at | Toronto FC | (49.96) | 0-2 |
| 06/07/08 | hosting | Colorado Rapids | (49.96) | 3-2 |
| 06/14/08 | at | San Jose Earthquakes | (49.65) | 3-0 |
| 06/21/08 | hosting | Columbus Crew | (50.41) | 3-3 |
| 06/29/08 | at | D.C. United | (49.88) | 1-4 |
| 07/04/08 | hosting | New England Revolution | (49.74) | 1-2 |
| 07/10/08 | hosting | Chivas USA | (49.94) | 1-1 |
| 07/19/08 | at | New York Red Bulls | (50.01) | 2-2 |
| 07/27/08 | at | FC Dallas | (50.07) | 0-4 |
| 08/03/08 | at | San Jose Earthquakes | (49.65) | 2-3 |
| 08/14/08 | at | Chivas USA | (49.94) | 2-2 |
| 08/21/08 | hosting | Chicago Fire | (50.13) | 0-1 |
| 08/30/08 | at | New England Revolution | (49.74) | 2-2 |
| 09/06/08 | hosting | Real Salt Lake | (49.95) | 2-2 |
| 09/13/08 | at | Kansas City Wizards | (49.85) | 0-2 |
| 09/20/08 | hosting | D.C. United | (49.88) | 5-2 |
| 09/25/08 | at | Chicago Fire | (50.13) | 1-3 |
| 10/04/08 | at | Columbus Crew | (50.41) | 0-1 |
| 10/12/08 | hosting | Colorado Rapids | (49.96) | 3-2 |
| 10/18/08 | at | Houston Dynamo | (50.04) | 0-3 |
| 10/26/08 | hosting | FC Dallas | (50.07) | 2-2 |