| (46.23) | ||||
| 09/09/07 | at | Minnesota | (51.57) | 3-24 |
| 09/16/07 | at | Jacksonville | (51.56) | 7-13 |
| 09/23/07 | hosting | Carolina | (48.46) | 20-27 |
| 09/30/07 | hosting | Houston | (50.56) | 26-16 |
| 10/07/07 | at | Tennessee | (50.72) | 13-20 |
| 10/15/07 | hosting | N.Y. Giants | (52.99) | 10-31 |
| 10/21/07 | at | New Orleans | (49.17) | 16-22 |
| 11/04/07 | hosting | San Francisco | (46.23) | 20-16 |
| 11/11/07 | at | Carolina | (48.46) | 20-13 |
| 11/18/07 | hosting | Tampa Bay | (49.10) | 7-31 |
| 11/22/07 | hosting | Indianapolis | (52.02) | 13-31 |
| 12/02/07 | at | St. Louis | (46.10) | 16-28 |
| 12/10/07 | hosting | New Orleans | (49.17) | 14-34 |
| 12/16/07 | at | Tampa Bay | (49.10) | 3-37 |
| 12/23/07 | at | Arizona | (48.49) | 27-30 OT |
| 12/30/07 | hosting | Seattle | (50.66) | 44-41 |