| 09/03/05 | at | Moravian | 31-22 |
| 09/10/05 | at | FDU-Florham | 49-3 |
| 09/17/05 | hosting | Wilkes | 17-14 |
| 09/24/05 | at | Lycoming | 31-13 |
| 10/01/05 | hosting | Lebanon Valley | 38-7 |
| 10/15/05 | hosting | Albright | 35-34 |
| 10/22/05 | at | Susquehanna | 48-14 |
| 10/29/05 | hosting | King's PA | 28-19 |
| 11/05/05 | at | Juniata | 58-27 |
| 11/12/05 | hosting | Widener | 36-21 |
| 11/19/05 | hosting | Curry | 37-22 |
| 11/26/05 | hosting | Hobart | 21-14 |
| 12/03/05 | hosting | Rowan | 21-27 |