| 09/03/05 | at | Salisbury | 28-48 |
| 09/10/05 | at | Guilford | 42-25 |
| 09/24/05 | hosting | North Carolina Wesleyan | 31-20 |
| 10/01/05 | hosting | Emory & Henry | 55-21 |
| 10/08/05 | at | Averett | 29-28 |
| 10/14/05 | at | Ferrum | 37-42 |
| 10/22/05 | hosting | Christopher Newport | 35-28 |
| 10/29/05 | at | Maryville | 28-24 |
| 11/05/05 | at | Greensboro | 45-21 |
| 11/12/05 | hosting | Shenandoah | 35-0 |