| 11/18/05 | hosting | Southern | 84-56 |
| 11/21/05 | hosting | Nicholls St. | 104-57 |
| 11/26/05 | at | West Virginia | 71-68 OT |
| 11/29/05 | hosting | Houston | 83-84 |
| 12/10/05 | hosting | McNeese St. | 90-70 |
| 12/13/05 | hosting | New Orleans | 94-53 |
| 12/17/05 | hosting | Louisiana Lafayette | 81-62 |
| 12/19/05 | hosting | Northern Iowa | 50-54 |
| 12/22/05 | vs. | Arkansas Monticello | 75-48 |
| 12/23/05 | vs. | Cincinnati | 72-75 |
| 12/31/05 | at | Ohio St. | 76-78 |
| 01/03/06 | hosting | Tulane | 75-58 |
| 01/07/06 | at | Connecticut | 66-67 |
| 01/11/06 | at | Arkansas | 63-58 |
| 01/14/06 | hosting | Tennessee | 88-74 |
| 01/18/06 | at | Mississippi St. | 71-57 |
| 01/21/06 | hosting | Alabama | 68-57 |
| 01/25/06 | hosting | Georgia | 81-52 |
| 01/28/06 | at | Mississippi | 79-73 |
| 02/01/06 | hosting | Auburn | 84-69 |
| 02/04/06 | at | Alabama | 62-67 |
| 02/08/06 | hosting | Arkansas | 78-77 |
| 02/11/06 | at | Florida | 62-71 |
| 02/15/06 | hosting | Mississippi St. | 72-59 |
| 02/18/06 | at | Auburn | 65-61 |
| 02/22/06 | at | Vanderbilt | 77-66 |
| 02/25/06 | hosting | Kentucky | 71-67 |
| 02/28/06 | at | South Carolina | 64-61 |
| 03/04/06 | hosting | Mississippi | 55-52 |
| 03/10/06 | at | Vanderbilt | 92-73 |
| 03/11/06 | vs. | Florida | 65-81 |
| 03/16/06 | vs. | Iona | 80-64 |
| 03/18/06 | vs. | Texas A&M | 58-57 |
| 03/23/06 | vs. | Duke | 62-54 |
| 03/25/06 | vs. | Texas | 70-60 OT |