| 11/02/05 | hosting | New Orleans/Okla Cty | 109-87 |
| 11/04/05 | at | San Antonio | 76-102 |
| 11/05/05 | at | Memphis | 106-113 |
| 11/07/05 | at | Toronto | 105-93 |
| 11/09/05 | hosting | Seattle | 112-85 |
| 11/11/05 | hosting | Memphis | 89-70 |
| 11/13/05 | at | Orlando | 108-100 OT |
| 11/15/05 | hosting | Washington | 114-99 |
| 11/18/05 | hosting | Orlando | 102-84 |
| 11/19/05 | at | Philadelphia | 123-120 |
| 11/22/05 | hosting | Boston | 115-93 |
| 11/24/05 | at | Indiana | 76-98 |
| 11/26/05 | hosting | Minnesota | 85-89 |
| 11/30/05 | hosting | L.A. Clippers | 112-105 OT |
| 12/02/05 | at | Seattle | 108-115 |
| 12/03/05 | at | L.A. Clippers | 90-102 |
| 12/06/05 | at | Sacramento | 102-97 |
| 12/09/05 | hosting | New Jersey | 100-109 |
| 12/10/05 | at | Milwaukee | 106-111 |
| 12/13/05 | hosting | Atlanta | 94-100 |
| 12/15/05 | hosting | Denver | 94-85 |
| 12/17/05 | hosting | Miami | 115-107 |
| 12/20/05 | hosting | Utah | 110-85 |
| 12/22/05 | at | Chicago | 108-100 |
| 12/23/05 | hosting | Indiana | 94-89 |
| 12/26/05 | hosting | Chicago | 102-91 |
| 12/27/05 | at | New Jersey | 91-96 |
| 12/31/05 | hosting | Detroit | 97-84 |
| 01/04/06 | at | Milwaukee | 91-84 |
| 01/05/06 | hosting | Houston | 81-90 |
| 01/07/06 | hosting | Milwaukee | 96-88 |
| 01/10/06 | hosting | New York | 84-92 |
| 01/12/06 | at | L.A. Lakers | 98-99 |
| 01/14/06 | at | Phoenix | 106-115 |
| 01/15/06 | at | Portland | 87-89 |
| 01/18/06 | at | Denver | 89-90 |
| 01/20/06 | at | Golden State | 79-99 |
| 01/21/06 | at | Utah | 108-90 |
| 01/24/06 | hosting | Indiana | 96-66 |
| 01/25/06 | at | Atlanta | 106-97 |
| 01/27/06 | at | Indiana | 93-89 |
| 01/29/06 | hosting | Phoenix | 113-106 |
| 01/30/06 | at | Charlotte | 103-91 |
| 02/01/06 | hosting | New Jersey | 91-85 |
| 02/02/06 | at | Miami | 73-101 |
| 02/04/06 | hosting | Philadelphia | 95-100 |
| 02/06/06 | hosting | Milwaukee | 89-86 |
| 02/08/06 | at | Minnesota | 97-91 |
| 02/10/06 | at | Washington | 89-101 |
| 02/11/06 | hosting | Golden State | 91-99 |
| 02/13/06 | hosting | San Antonio | 101-87 |
| 02/15/06 | at | Boston | 113-109 2OT |
| 02/21/06 | hosting | Orlando | 105-92 |
| 02/22/06 | at | Philadelphia | 107-116 |
| 02/24/06 | hosting | Washington | 94-102 |
| 02/26/06 | at | Detroit | 78-90 |
| 02/27/06 | hosting | Detroit | 72-84 |
| 03/01/06 | hosting | Sacramento | 90-97 |
| 03/02/06 | at | Chicago | 92-91 |
| 03/05/06 | hosting | Chicago | 91-72 |
| 03/07/06 | hosting | Toronto | 106-99 |
| 03/08/06 | at | Toronto | 98-97 |
| 03/10/06 | at | Orlando | 73-102 |
| 03/12/06 | at | Miami | 92-98 |
| 03/14/06 | at | Dallas | 87-91 |
| 03/17/06 | hosting | Portland | 99-84 |
| 03/19/06 | hosting | L.A. Lakers | 96-95 |
| 03/22/06 | hosting | Charlotte | 120-118 OT |
| 03/24/06 | hosting | Boston | 94-82 |
| 03/26/06 | at | Houston | 104-102 OT |
| 03/29/06 | hosting | Dallas | 107-94 |
| 04/01/06 | hosting | Miami | 106-99 |
| 04/02/06 | at | Charlotte | 101-97 |
| 04/04/06 | hosting | Philadelphia | 124-91 |
| 04/05/06 | at | New York | 94-96 |
| 04/08/06 | at | New Jersey | 108-102 |
| 04/10/06 | at | New Orleans/Okla Cty | 103-101 |
| 04/12/06 | at | Detroit | 73-96 |
| 04/13/06 | hosting | New York | 91-87 |
| 04/16/06 | at | Washington | 92-104 |
| 04/17/06 | at | Boston | 93-88 |
| 04/19/06 | hosting | Atlanta | 100-99 |
| 04/22/06 | hosting | Washington | 97-86 |
| 04/25/06 | hosting | Washington | 84-89 |
| 04/28/06 | at | Washington | 97-96 |
| 04/30/06 | at | Washington | 96-106 |
| 05/03/06 | hosting | Washington | 121-120 OT |
| 05/05/06 | at | Washington | 114-113 OT |
| 05/07/06 | at | Detroit | 86-113 |
| 05/09/06 | at | Detroit | 92-97 |
| 05/13/06 | hosting | Detroit | 86-77 |
| 05/15/06 | hosting | Detroit | 74-72 |
| 05/17/06 | at | Detroit | 86-84 |
| 05/19/06 | hosting | Detroit | 82-84 |
| 05/21/06 | at | Detroit | 61-79 |