| 09/03/05 | hosting | Texas A&M | 25-24 |
| 09/10/05 | at | Maryland | 28-24 |
| 09/17/05 | hosting | Miami FL | 30-36 OT |
| 09/24/05 | hosting | Boston College | 13-16 OT |
| 10/01/05 | at | Wake Forest | 27-31 |
| 10/13/05 | at | North Carolina State | 31-10 |
| 10/22/05 | hosting | Temple | 37-7 |
| 10/29/05 | at | Georgia Tech | 9-10 |
| 11/05/05 | hosting | Duke | 49-20 |
| 11/12/05 | hosting | Florida State | 35-14 |
| 11/19/05 | at | South Carolina | 13-9 |
| 12/27/05 | vs. | Colorado | 19-10 |