| 09/10/05 | at | SE Louisiana St | 21-48 |
| 09/17/05 | hosting | Langston | 24-7 |
| 09/24/05 | at | Alabama St | 3-38 |
| 10/01/05 | hosting | Arkansas-Pine Bluff | 7-17 |
| 10/08/05 | hosting | Prairie View A&M | 22-10 |
| 10/15/05 | at | Texas Southern | 29-22 |
| 10/22/05 | at | Southern U. | 38-16 |
| 11/05/05 | hosting | Mississippi Valley St | 38-36 |
| 11/12/05 | hosting | Alabama A&M | 21-28 |
| 11/19/05 | at | Jackson State | 31-14 |
| 12/03/05 | hosting | Grambling State | 19-46 |