| 09/03/05 | vs. | Hampton | 7-20 |
| 09/10/05 | vs. | Tennessee State | 14-20 |
| 09/17/05 | hosting | Texas Southern | 24-21 |
| 09/24/05 | at | Mississippi Valley St | 33-14 |
| 10/08/05 | hosting | Alabama St | 23-44 |
| 10/15/05 | at | Southern U. | 14-20 |
| 10/22/05 | hosting | Grambling State | 21-52 |
| 10/29/05 | hosting | Arkansas-Pine Bluff | 36-64 |
| 11/05/05 | at | Alabama A&M | 6-52 |
| 11/12/05 | at | Prairie View A&M | 9-27 |
| 11/19/05 | hosting | Alcorn St | 14-31 |