| 09/10/05 | at | Mississippi Valley St | 28-31 |
| 09/17/05 | hosting | Prairie View A&M | 38-0 |
| 10/01/05 | vs. | Alabama St | 35-45 |
| 10/08/05 | hosting | Alabama A&M | 7-20 |
| 10/15/05 | hosting | Jackson State | 20-14 |
| 10/22/05 | hosting | Alcorn St | 16-38 |
| 11/05/05 | at | Texas Southern | 44-20 |
| 11/12/05 | at | Arkansas-Pine Bluff | 27-21 |
| 11/26/05 | vs. | Grambling State | 35-50 |