| 09/01/05 | hosting | Temple | 63-16 |
| 09/10/05 | hosting | LSU | 31-35 |
| 09/17/05 | hosting | Northwestern | 52-21 |
| 09/24/05 | at | Oregon State | 42-24 |
| 10/01/05 | hosting | Southern Cal | 28-38 |
| 10/08/05 | hosting | Oregon | 17-31 |
| 10/22/05 | at | Stanford | 35-45 |
| 10/29/05 | hosting | Washington | 44-20 |
| 11/05/05 | at | Washington State | 27-24 |
| 11/12/05 | at | UCLA | 35-45 |
| 11/25/05 | hosting | Arizona | 23-20 |
| 12/27/05 | vs. | Rutgers | 45-40 |