| 09/03/05 | at | Rochester | 9-7 |
| 09/10/05 | hosting | Randolph-Macon | 24-0 |
| 09/17/05 | at | Carnegie Mellon | 9-6 |
| 10/01/05 | at | Dickinson | 35-14 |
| 10/08/05 | hosting | Franklin & Marshall | 19-7 |
| 10/14/05 | hosting | Gettysburg | 14-0 |
| 10/22/05 | at | Muhlenberg | 13-10 |
| 10/29/05 | hosting | Ursinus | 17-21 |
| 11/05/05 | at | Hampden-Sydney | 20-49 |
| 11/12/05 | at | McDaniel | 14-5 |
| 11/19/05 | at | Thiel | 3-28 |