| 09/03/05 | at | Wilmington | 21-18 |
| 09/10/05 | at | Rose-Hulman | 49-7 |
| 09/17/05 | hosting | Kalamazoo | 42-0 |
| 10/01/05 | hosting | Hanover | 35-41 |
| 10/08/05 | hosting | Franklin | 41-20 |
| 10/15/05 | at | Manchester | 28-7 |
| 10/22/05 | hosting | Defiance | 40-19 |
| 10/29/05 | at | Bluffton | 56-14 |
| 11/05/05 | at | Anderson | 17-7 |
| 11/12/05 | hosting | Thomas More | 31-7 |
| 11/19/05 | at | Mount Union | 6-49 |