| 09/03/05 | at | Otterbein | 0-14 |
| 09/10/05 | hosting | Adrian | 0-37 |
| 09/17/05 | hosting | Bethany WV | 29-26 |
| 10/01/05 | at | Case Western Reserve | 14-13 |
| 10/08/05 | at | Anderson | 32-7 |
| 10/15/05 | hosting | Hanover | 28-14 |
| 10/22/05 | at | Mt St Joseph | 19-40 |
| 10/29/05 | hosting | Franklin | 38-23 |
| 11/05/05 | hosting | Manchester | 29-32 |
| 11/12/05 | at | Bluffton | 41-14 |