| 09/03/05 | hosting | Thomas More | 12-7 |
| 09/10/05 | at | Wash & Jeff | 20-56 |
| 09/17/05 | hosting | Bridgewater VA | 42-56 |
| 09/24/05 | at | Waynesburg | 17-34 |
| 10/01/05 | at | Mt St Joseph | 41-35 |
| 10/08/05 | hosting | Manchester | 48-7 |
| 10/15/05 | at | Defiance | 14-28 |
| 10/22/05 | hosting | Bluffton | 19-33 |
| 10/29/05 | at | Anderson | 35-28 |
| 11/12/05 | hosting | Franklin | 15-45 |