| 09/03/05 | at | Centre | 20-27 |
| 09/10/05 | at | Hiram | 31-6 |
| 09/17/05 | hosting | Thiel | 0-42 |
| 09/24/05 | hosting | Adrian | 21-45 |
| 10/01/05 | at | Manchester | 59-7 |
| 10/15/05 | hosting | Anderson | 10-13 |
| 10/22/05 | at | Hanover | 33-19 |
| 10/29/05 | hosting | Mt St Joseph | 14-56 |
| 11/05/05 | at | Franklin | 21-24 |
| 11/12/05 | hosting | Defiance | 14-41 |