| 09/03/05 | at | Denison | 17-21 |
| 09/17/05 | hosting | Manchester | 28-7 |
| 09/24/05 | hosting | Hanover | 34-17 |
| 10/01/05 | at | Thomas More | 7-13 |
| 10/08/05 | at | Bethany WV | 38-21 |
| 10/15/05 | hosting | Thiel | 28-35 |
| 10/22/05 | at | Grove City | 6-7 |
| 10/29/05 | hosting | Wash & Jeff | 24-35 |
| 11/05/05 | at | Frostburg St | 10-17 |
| 11/12/05 | hosting | Westminster PA | 40-13 |