| 09/03/05 | at | Mississippi State | 6-38 |
| 09/17/05 | hosting | Indiana State | 27-15 |
| 09/24/05 | at | Illinois St | 0-42 |
| 10/01/05 | at | Tennessee Tech | 21-42 |
| 10/08/05 | hosting | Jacksonville State | 23-28 |
| 10/15/05 | at | Samford | 23-27 |
| 10/22/05 | hosting | Eastern Illinois | 28-35 |
| 10/29/05 | at | SE Missouri St | 21-52 |
| 11/05/05 | hosting | Eastern Kentucky | 7-43 |
| 11/12/05 | hosting | Austin Peay | 42-6 |
| 11/17/05 | at | Tennessee-Martin | 20-49 |