| 11/19/05 | hosting | Northern Illinois | 87-51 |
| 11/26/05 | at | Arkansas St. | 97-80 |
| 12/02/05 | hosting | Georgia Southern | 101-55 |
| 12/03/05 | hosting | Texas A&M Corpus Chris | 95-75 |
| 12/07/05 | at | Oral Roberts | 88-76 |
| 12/10/05 | hosting | Detroit | 85-71 |
| 12/15/05 | at | Arkansas | 75-79 |
| 12/22/05 | hosting | Arkansas St. | 84-55 |
| 12/28/05 | at | Creighton | 56-78 |
| 12/30/05 | hosting | Indiana St. | 97-78 |
| 01/02/06 | at | Drake | 85-79 |
| 01/05/06 | at | Evansville | 80-65 |
| 01/07/06 | hosting | Northern Iowa | 62-72 |
| 01/11/06 | hosting | Illinois St. | 70-54 |
| 01/14/06 | at | Wichita St. | 57-81 |
| 01/19/06 | hosting | Southern Illinois | 71-63 |
| 01/22/06 | hosting | Wichita St. | 62-68 |
| 01/25/06 | at | Bradley | 76-86 |
| 01/29/06 | at | Indiana St. | 80-58 |
| 02/01/06 | hosting | Drake | 84-59 |
| 02/04/06 | hosting | Bradley | 70-62 |
| 02/07/06 | at | Southern Illinois | 64-66 |
| 02/11/06 | at | Northern Iowa | 66-63 |
| 02/14/06 | hosting | Evansville | 71-50 |
| 02/18/06 | at | Wisconsin Milwaukee | 72-63 |
| 02/22/06 | at | Illinois St. | 72-61 |
| 02/25/06 | hosting | Creighton | 60-54 |
| 03/03/06 | vs. | Northern Iowa | 42-57 |
| 03/17/06 | hosting | Stanford | 76-67 |
| 03/20/06 | hosting | Houston | 60-59 |
| 03/22/06 | at | Louisville | 56-74 |