| 11/19/05 | hosting | Tennessee Martin | 78-61 |
| 12/03/05 | hosting | Prairie View A&M | 90-65 |
| 12/04/05 | hosting | Arkansas St. | 67-55 |
| 12/05/05 | hosting | Richmond | 53-45 |
| 12/10/05 | hosting | Akron | 111-85 |
| 12/13/05 | hosting | Chicago St. | 78-54 |
| 12/17/05 | at | Kentucky | 61-73 |
| 12/20/05 | hosting | Middle Tennessee | 76-68 |
| 12/21/05 | hosting | College of Charleston | 78-63 |
| 12/24/05 | hosting | Detroit | 56-48 |
| 12/28/05 | hosting | Fairleigh Dickinson | 89-66 |
| 12/31/05 | vs. | Miami FL | 58-43 |
| 01/05/06 | hosting | Villanova | 67-76 |
| 01/07/06 | at | Providence | 72-67 |
| 01/09/06 | hosting | UC Davis | 81-58 |
| 01/15/06 | hosting | Pittsburgh | 57-61 |
| 01/17/06 | at | St. John's | 56-68 |
| 01/21/06 | hosting | Connecticut | 58-71 |
| 01/25/06 | hosting | Cincinnati | 67-50 |
| 01/28/06 | at | Rutgers | 56-65 |
| 01/30/06 | at | Villanova | 73-79 |
| 02/04/06 | hosting | Notre Dame | 89-86 OT |
| 02/06/06 | at | Cincinnati | 68-74 |
| 02/11/06 | hosting | South Florida | 57-54 |
| 02/18/06 | at | Syracuse | 66-79 |
| 02/22/06 | hosting | DePaul | 65-53 |
| 02/25/06 | at | West Virginia | 64-68 |
| 03/01/06 | hosting | Marquette | 67-60 OT |
| 03/04/06 | at | Connecticut | 80-84 |
| 03/08/06 | vs. | Pittsburgh | 56-61 |
| 03/17/06 | hosting | Delaware St. | 71-54 |
| 03/20/06 | hosting | Clemson | 74-68 |
| 03/22/06 | hosting | Missouri St. | 74-56 |
| 03/28/06 | vs. | South Carolina | 63-78 |