| 08/27/05 | at | Western St | 26-7 |
| 09/01/05 | hosting | Southern Nazarene | 42-7 |
| 09/10/05 | at | SE Oklahoma St | 27-24 |
| 09/17/05 | hosting | Central Oklahoma | 20-16 |
| 09/24/05 | hosting | Midwestern St | 30-29 |
| 10/01/05 | at | Eastern New Mexico | 14-38 |
| 10/08/05 | hosting | Abilene Christian | 27-24 |
| 10/15/05 | hosting | Northeastern St OK | 49-20 |
| 10/22/05 | at | West Texas A&M | 58-53 |
| 10/29/05 | hosting | Tarleton St | 17-30 |
| 11/05/05 | at | TAMU-Kingsville | 54-51 |
| 11/12/05 | hosting | NW Missouri St | 14-45 |