| 09/02/06 | hosting | Marshall | 42-10 |
| 09/09/06 | hosting | Eastern Washington | 52-3 |
| 09/14/06 | hosting | Maryland | 45-24 |
| 09/23/06 | at | East Carolina | 27-10 |
| 10/07/06 | at | Mississippi St | 42-14 |
| 10/14/06 | hosting | Syracuse | 41-17 |
| 10/20/06 | at | Connecticut | 37-11 |
| 11/02/06 | at | Louisville | 34-44 |
| 11/11/06 | hosting | Cincinnati | 42-24 |
| 11/16/06 | at | Pittsburgh | 45-27 |
| 11/25/06 | hosting | South Florida | 19-24 |
| 12/02/06 | hosting | Rutgers | 41-39 OT |
| 01/01/07 | at | Georgia Tech | 38-35 |