| 11/14/05 | hosting | Manhattan | 66-52 |
| 11/16/05 | at | Duke | 40-93 |
| 11/19/05 | hosting | Marist | 75-72 |
| 11/28/05 | hosting | St. Peter's | 66-57 |
| 12/01/05 | at | Richmond | 49-60 |
| 12/05/05 | hosting | Fairleigh Dickinson | 65-57 |
| 12/08/05 | hosting | Monmouth | 61-45 |
| 12/11/05 | hosting | Tulane | 83-64 |
| 12/18/05 | hosting | Northwestern | 42-44 |
| 12/29/05 | hosting | Morgan St. | 93-46 |
| 12/31/05 | hosting | Iona | 73-59 |
| 01/04/06 | hosting | St. John's | 69-61 OT |
| 01/07/06 | at | Rutgers | 78-82 |
| 01/11/06 | hosting | Marquette | 63-67 |
| 01/17/06 | at | Villanova | 64-73 |
| 01/20/06 | hosting | South Florida | 94-89 OT |
| 01/25/06 | at | North Carolina St. | 83-65 |
| 01/29/06 | at | Syracuse | 68-61 |
| 02/01/06 | at | Providence | 77-74 |
| 02/05/06 | hosting | Rutgers | 73-67 |
| 02/08/06 | at | South Florida | 70-65 |
| 02/11/06 | hosting | Connecticut | 57-99 |
| 02/14/06 | hosting | West Virginia | 71-64 |
| 02/18/06 | hosting | Notre Dame | 91-102 |
| 02/21/06 | at | St. John's | 47-58 |
| 02/25/06 | at | DePaul | 64-67 |
| 02/28/06 | hosting | Cincinnati | 72-62 |
| 03/03/06 | at | Pittsburgh | 65-61 |
| 03/08/06 | vs. | Rutgers | 48-61 |
| 03/16/06 | vs. | Wichita St. | 66-86 |