| (48.19) | ||||
| 09/07/08 | hosting | Dallas | (50.99) | 10-28 |
| 09/14/08 | hosting | Pittsburgh | (52.96) | 6-10 |
| 09/21/08 | at | Baltimore | (53.80) | 10-28 |
| 09/28/08 | at | Cincinnati | (49.17) | 20-12 |
| 10/13/08 | hosting | N.Y. Giants | (52.60) | 35-14 |
| 10/19/08 | at | Washington | (49.68) | 11-14 |
| 10/26/08 | at | Jacksonville | (48.04) | 23-17 |
| 11/02/08 | hosting | Baltimore | (53.80) | 27-37 |
| 11/06/08 | hosting | Denver | (48.23) | 30-34 |
| 11/17/08 | at | Buffalo | (48.28) | 29-27 |
| 11/23/08 | hosting | Houston | (50.33) | 6-16 |
| 11/30/08 | hosting | Indianapolis | (52.44) | 6-10 |
| 12/07/08 | at | Tennessee | (52.47) | 9-28 |
| 12/15/08 | at | Philadelphia | (52.53) | 10-30 |
| 12/21/08 | hosting | Cincinnati | (49.17) | 0-14 |
| 12/28/08 | at | Pittsburgh | (52.96) | 0-31 |