| 10/08/05 | at | Maine | 1-3 |
| 10/09/05 | at | Maine | 1-4 |
| 10/21/05 | hosting | Rensselaer | 1-2 |
| 10/22/05 | hosting | Rensselaer | 1-3 |
| 10/29/05 | at | Harvard | 0-7 |
| 11/05/05 | at | Vermont | 2-1 |
| 11/06/05 | at | Vermont | 1-3 |
| 11/11/05 | at | Colgate | 0-9 |
| 11/26/05 | at | Boston University | 1-3 |
| 11/27/05 | at | Boston University | 1-5 |
| 12/09/05 | hosting | Mercyhurst | 1-5 |
| 12/10/05 | hosting | Mercyhurst | 1-9 |
| 01/07/06 | at | Clarkson | 0-6 |
| 01/08/06 | at | Elmira | 1-4 |
| 01/14/06 | at | Union | 2-2 OT |
| 01/15/06 | at | Union | 2-3 OT |
| 01/20/06 | at | Quinnipiac | 3-4 |
| 01/21/06 | at | Quinnipiac | 2-4 |
| 01/27/06 | hosting | Wayne State | 2-4 |
| 01/28/06 | hosting | Wayne State | 1-4 |
| 02/04/06 | hosting | Niagara | 0-0 OT |
| 02/05/06 | hosting | Niagara | 1-0 |
| 02/11/06 | at | Niagara | 1-8 |
| 02/12/06 | at | Niagara | 4-3 |
| 02/17/06 | hosting | Sacred Heart | 3-1 |
| 02/18/06 | hosting | Sacred Heart | 7-3 |
| 02/24/06 | at | Wayne State | 0-7 |
| 02/25/06 | at | Wayne State | 0-7 |
| 03/03/06 | at | Mercyhurst | 1-3 |
| 03/04/06 | at | Mercyhurst | 0-5 |
| 03/09/06 | vs. | Mercyhurst | 0-9 |