| 10/07/05 | at | Bemidji State | 1-1 OT |
| 10/08/05 | at | Bemidji State | 1-2 |
| 10/14/05 | hosting | St. Lawrence | 2-3 |
| 10/15/05 | hosting | St. Lawrence | 0-4 |
| 10/21/05 | hosting | Clarkson | 0-2 |
| 10/22/05 | hosting | Clarkson | 1-1 OT |
| 10/28/05 | at | Colgate | 2-3 |
| 10/29/05 | at | Colgate | 4-0 |
| 11/04/05 | hosting | Connecticut | 1-0 |
| 11/05/05 | hosting | Connecticut | 3-2 |
| 11/11/05 | at | Minnesota State | 2-3 |
| 11/12/05 | at | Minnesota State | 1-5 |
| 11/19/05 | at | Cornell | 5-4 |
| 11/20/05 | at | Cornell | 4-5 OT |
| 11/25/05 | hosting | St. Cloud State | 3-2 |
| 11/26/05 | hosting | St. Cloud State | 4-3 |
| 12/09/05 | at | Princeton | 2-5 |
| 12/10/05 | at | Princeton | 2-2 OT |
| 01/06/06 | hosting | Wisconsin | 3-5 |
| 01/07/06 | hosting | Wisconsin | 0-3 |
| 01/13/06 | at | Mercyhurst | 2-2 OT |
| 01/14/06 | at | Mercyhurst | 2-4 |
| 01/20/06 | hosting | Rensselaer | 2-1 |
| 01/21/06 | hosting | Rensselaer | 4-2 |
| 01/27/06 | at | Robert Morris | 4-2 |
| 01/28/06 | at | Robert Morris | 4-1 |
| 02/10/06 | hosting | Mercyhurst | 2-4 |
| 02/11/06 | hosting | Mercyhurst | 2-2 OT |
| 02/17/06 | hosting | Niagara | 4-0 |
| 02/18/06 | hosting | Niagara | 2-1 |
| 02/24/06 | hosting | Robert Morris | 7-0 |
| 02/25/06 | hosting | Robert Morris | 7-0 |
| 03/03/06 | at | Niagara | 2-3 |
| 03/04/06 | at | Niagara | 1-2 OT |
| 03/09/06 | hosting | Niagara | 3-4 OT |