| 10/14/05 | hosting | Rensselaer | 2-3 OT |
| 10/15/05 | at | Rensselaer | 1-1 OT |
| 10/22/05 | at | Providence | 1-1 OT |
| 10/23/05 | at | Providence | 1-4 |
| 10/28/05 | hosting | Wayne State | 3-2 |
| 10/29/05 | hosting | Wayne State | 0-4 |
| 11/04/05 | hosting | Brown | 3-0 |
| 11/05/05 | hosting | Yale | 4-2 |
| 11/11/05 | hosting | Robert Morris | 9-0 |
| 11/19/05 | hosting | Niagara | 3-1 |
| 11/20/05 | hosting | Niagara | 2-4 |
| 11/26/05 | hosting | Cornell | 3-1 |
| 11/27/05 | at | Cornell | 3-1 |
| 12/02/05 | at | Quinnipiac | 1-1 OT |
| 12/03/05 | at | Princeton | 2-6 |
| 01/04/06 | at | New Hampshire | 0-7 |
| 01/07/06 | hosting | Harvard | 1-5 |
| 01/08/06 | hosting | Dartmouth | 2-2 OT |
| 01/13/06 | hosting | Princeton | 1-2 |
| 01/14/06 | hosting | Quinnipiac | 4-0 |
| 01/20/06 | at | Clarkson | 1-3 |
| 01/21/06 | at | St. Lawrence | 3-0 |
| 01/27/06 | at | Yale | 3-3 OT |
| 01/28/06 | at | Brown | 0-3 |
| 02/03/06 | at | Mercyhurst | 2-2 OT |
| 02/04/06 | at | Mercyhurst | 1-1 OT |
| 02/10/06 | hosting | St. Lawrence | 1-4 |
| 02/11/06 | hosting | Clarkson | 2-0 |
| 02/17/06 | at | Dartmouth | 1-2 |
| 02/18/06 | at | Harvard | 0-3 |
| 02/24/06 | hosting | Union | 6-1 |
| 02/25/06 | hosting | Union | 9-0 |
| 03/03/06 | at | Princeton | 0-3 |
| 03/04/06 | at | Princeton | 4-5 |