| 10/15/05 | hosting | Maine | 4-1 |
| 10/21/05 | at | Niagara | 6-0 |
| 10/22/05 | at | Niagara | 8-2 |
| 10/28/05 | hosting | Brown | 5-1 |
| 10/30/05 | at | Brown | 2-3 |
| 11/04/05 | hosting | Boston College | 4-0 |
| 11/05/05 | at | Boston College | 2-3 OT |
| 11/13/05 | at | Yale | 5-2 |
| 11/19/05 | at | Northeastern | 8-2 |
| 11/22/05 | hosting | Northeastern | 2-0 |
| 11/27/05 | vs. | Wisconsin | 2-1 |
| 11/30/05 | hosting | Boston University | 5-0 |
| 12/04/05 | at | Vermont | 4-1 |
| 12/10/05 | at | Harvard | 3-0 |
| 01/01/06 | at | Dartmouth | 4-1 |
| 01/04/06 | hosting | Colgate | 7-0 |
| 01/07/06 | at | Boston University | 5-1 |
| 01/11/06 | hosting | Harvard | 5-1 |
| 01/13/06 | at | Maine | 5-5 OT |
| 01/14/06 | at | Maine | 5-3 |
| 01/20/06 | hosting | Dartmouth | 3-1 |
| 01/22/06 | hosting | Connecticut | 3-0 |
| 01/27/06 | hosting | Mercyhurst | 2-1 |
| 01/29/06 | hosting | Providence | 7-2 |
| 02/01/06 | at | Providence | 2-1 |
| 02/04/06 | at | Boston College | 6-1 |
| 02/11/06 | at | Northeastern | 11-1 |
| 02/12/06 | hosting | Providence | 4-1 |
| 02/17/06 | at | Connecticut | 5-1 |
| 02/19/06 | hosting | Connecticut | 6-0 |
| 02/22/06 | hosting | Boston University | 6-0 |
| 02/25/06 | hosting | Vermont | 5-0 |
| 02/26/06 | hosting | Vermont | 8-0 |
| 03/04/06 | vs. | Maine | 6-0 |
| 03/05/06 | vs. | Boston College | 6-0 |
| 03/17/06 | hosting | Harvard | 3-1 |
| 03/24/06 | vs. | Minnesota | 4-5 |