| 10/07/05 | at | Minnesota | 0-3 |
| 10/15/05 | hosting | Providence | 3-1 |
| 10/22/05 | at | Maine | 0-1 OT |
| 10/29/05 | hosting | Yale | 3-0 |
| 10/30/05 | hosting | Quinnipiac | 2-3 |
| 11/04/05 | at | Wayne State | 0-1 |
| 11/05/05 | at | Wayne State | 2-3 |
| 11/12/05 | hosting | Boston University | 3-0 |
| 11/13/05 | at | Northeastern | 2-3 |
| 11/19/05 | at | Boston College | 1-2 |
| 11/20/05 | at | Boston University | 1-0 OT |
| 11/25/05 | at | St. Lawrence | 1-6 |
| 11/26/05 | at | St. Lawrence | 0-4 |
| 12/01/05 | hosting | Vermont | 4-0 |
| 12/03/05 | hosting | Boston College | 1-6 |
| 12/06/05 | hosting | Brown | 0-1 |
| 12/08/05 | at | Harvard | 1-3 |
| 01/01/06 | at | Vermont | 2-1 |
| 01/02/06 | at | Vermont | 3-0 |
| 01/07/06 | hosting | Mercyhurst | 0-4 |
| 01/08/06 | hosting | Niagara | 8-0 |
| 01/12/06 | hosting | Rensselaer | 1-2 |
| 01/14/06 | at | Dartmouth | 1-1 OT |
| 01/15/06 | at | Boston University | 0-3 |
| 01/22/06 | at | New Hampshire | 0-3 |
| 01/28/06 | at | Northeastern | 3-2 |
| 01/29/06 | hosting | Northeastern | 10-1 |
| 02/04/06 | hosting | Maine | 5-1 |
| 02/05/06 | hosting | Maine | 1-2 |
| 02/11/06 | hosting | Boston College | 0-4 |
| 02/17/06 | hosting | New Hampshire | 1-5 |
| 02/19/06 | at | New Hampshire | 0-6 |
| 02/25/06 | hosting | Providence | 2-1 |
| 02/26/06 | at | Providence | 2-5 |