| 10/28/05 | at | New Hampshire | 1-5 |
| 10/30/05 | hosting | New Hampshire | 3-2 |
| 11/04/05 | at | Colgate | 0-3 |
| 11/05/05 | at | Cornell | 3-2 |
| 11/12/05 | at | Minnesota | 1-5 |
| 11/13/05 | at | Minnesota | 0-3 |
| 11/18/05 | hosting | Dartmouth | 2-0 |
| 11/19/05 | hosting | Harvard | 1-1 OT |
| 11/25/05 | hosting | Niagara | 1-2 |
| 11/26/05 | at | Providence | 3-5 |
| 11/29/05 | at | Northeastern | 2-4 |
| 12/06/05 | at | Connecticut | 1-0 |
| 01/06/06 | hosting | Quinnipiac | 4-0 |
| 01/07/06 | hosting | Princeton | 4-3 |
| 01/13/06 | at | Clarkson | 1-0 |
| 01/14/06 | at | St. Lawrence | 1-4 |
| 01/18/06 | hosting | Boston University | 2-2 OT |
| 01/20/06 | at | Union | 6-0 |
| 01/21/06 | at | Union | 3-2 |
| 01/24/06 | at | Yale | 3-1 |
| 01/27/06 | hosting | Cornell | 1-3 |
| 01/28/06 | hosting | Colgate | 3-0 |
| 02/03/06 | at | Harvard | 0-0 OT |
| 02/04/06 | at | Dartmouth | 3-3 OT |
| 02/14/06 | hosting | Yale | 1-3 |
| 02/17/06 | hosting | St. Lawrence | 2-5 |
| 02/18/06 | hosting | Clarkson | 3-1 |
| 02/24/06 | at | Princeton | 2-3 |
| 02/25/06 | at | Quinnipiac | 3-3 OT |
| 03/03/06 | hosting | Dartmouth | 4-2 |
| 03/04/06 | hosting | Dartmouth | 3-0 |
| 03/11/06 | vs. | Princeton | 1-0 |
| 03/12/06 | vs. | Harvard | 3-4 |