| 10/07/05 | at | Northeastern | 3-4 |
| 10/11/05 | hosting | Quinnipiac | 2-2 OT |
| 10/14/05 | hosting | Union | 4-1 |
| 10/15/05 | hosting | Union | 6-2 |
| 10/18/05 | hosting | Boston College | 3-3 OT |
| 10/22/05 | at | Vermont | 3-3 OT |
| 10/23/05 | at | Vermont | 4-1 |
| 10/26/05 | at | Northeastern | 4-2 |
| 10/29/05 | at | Dartmouth | 3-4 |
| 11/04/05 | at | Rensselaer | 3-7 |
| 11/05/05 | at | Rensselaer | 3-5 |
| 11/12/05 | at | Connecticut | 0-3 |
| 11/13/05 | hosting | Vermont | 3-1 |
| 11/19/05 | at | Providence | 0-4 |
| 11/20/05 | hosting | Connecticut | 0-1 OT |
| 11/26/05 | hosting | Robert Morris | 3-1 |
| 11/27/05 | hosting | Robert Morris | 5-1 |
| 11/30/05 | at | New Hampshire | 0-5 |
| 12/03/05 | hosting | Providence | 2-1 |
| 12/04/05 | hosting | Sacred Heart | 7-2 |
| 01/07/06 | hosting | New Hampshire | 1-5 |
| 01/15/06 | hosting | Connecticut | 3-0 |
| 01/18/06 | at | Brown | 2-2 OT |
| 01/21/06 | at | Boston College | 2-5 |
| 01/22/06 | hosting | Boston College | 1-2 |
| 01/28/06 | at | Maine | 0-7 |
| 02/04/06 | hosting | Northeastern | 3-4 |
| 02/07/06 | at | Harvard | 1-2 OT |
| 02/11/06 | at | Providence | 1-6 |
| 02/14/06 | vs. | Northeastern | 3-1 |
| 02/18/06 | hosting | Maine | 2-1 |
| 02/19/06 | hosting | Maine | 1-2 |
| 02/22/06 | at | New Hampshire | 0-6 |