| 09/01/05 | hosting | William & Mary | 36-24 |
| 09/10/05 | hosting | Kansas St | 19-21 |
| 09/24/05 | at | Central Florida | 13-23 |
| 10/01/05 | hosting | SMU | 16-13 OT |
| 10/08/05 | at | Virginia Tech | 14-41 |
| 10/15/05 | hosting | Alabama-Birmingham | 20-19 |
| 10/22/05 | at | UTEP | 3-31 |
| 10/29/05 | vs. | Tulane | 27-26 |
| 11/08/05 | hosting | Southern Miss | 24-27 OT |
| 11/19/05 | hosting | East Carolina | 29-34 |
| 11/26/05 | at | Memphis | 3-26 |